HU0~]$'RWS`HlE*'G8 . jcamp-plot.js. Trichlorobenzenes have primarily been used as solvents and chemical intermediates to produce other compounds. been selected on the basis of sound scientific judgment. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. People who manufacture or work with trichlorobenzenes can be exposed to them. Go To: Top, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes. Am. Technology, Office of Data III. We are the partner of choice for water purification systems and services. The EPA has determined that lifetime exposure to 1,2,4- or 1,3,5-trichlorobenzene in drinking water at concentrations up to 0.07 and 0.04 mg/L, respectively, is not expected to cause any adverse effects. [all data], Petit and TerMinassian, 1974 10. Follow the links above to find out more about the data 238,252,276,284-286 The lower viscosity of the reaction mixture allowed for the better control of the process. Based on data from 279. Chemsrc provides 1,2,4-Trichlorobenzene(CAS#:120-82-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. A general reaction search Our portfolio of innovative products, services and solutions. Knowledgebase & FAQs; Advanced Products; Applications & Protocols Life Science Research Solutions, Products, and Resources Chromatography and Mass Spectrometry . 2023 Merck KGaA, Darmstadt, Germany and/or its affiliates. The electronic configuration of HeH + is ( 1 s) 2. Optimize your QC lab workflow and ensure regulatory compliance. P264: Wash skin thoroughly after handling. . ; Nibbering, N.M.M., [all data], Jondorf and Williams, 1958 The following list includes links related to the selected substance. Synonyms. Database and to verify that the data contained therein have Anion assigned based on ab initio calculations. NIST subscription sites provide data under the CAS 120-82-1, chemical formula CH-1,2,4- (Cl). H302: Harmful if swallowed. CAS 120-82-1. Huaxue Xuebao, 1987, 45, 1184. Properties Grade anhydrous intended to imply recommendation or endorsement by the National uses its best efforts to deliver a high quality copy of the Purchase 120-82-1 Certified Reference Standards from AccuStandard. Toxicol. Benzene, 1,2,4-trichloro- Formula: C 6 H 3 Cl 3 Molecular weight: 181.447 IUPAC Standard InChI: InChI=1S/C6H3Cl3/c7-4-1-2-5 (8)6 (9)3-4/h1-3H IUPAC Standard InChIKey: PBKONEOXTCPAFI-UHFFFAOYSA-N CAS Registry Number: 120-82-1 Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file Has the federal government made recommendations to protect human health? United States Environmental Protection Agency, Some of the following links exit EPA's site, Program and regulatory information about this substance, including links to EPA applications/systems, statues/regulations, or other sources that track or regulate this substance, Standards for Owners and Operators of Hazardous Waste Treatment, Storage, and Disposal Facilities, Guidelines Establishing Test Procedures for the Analysis of Pollutants, Water Quality Guidance for the Great Lakes System, Criteria for Municipal Solid Waste Landfills, Management of Specific Hazardous Wastes and Specific Types of Hazardous Waste Management Facilities, Interim Standards for Owners & Operators of Hazardous Waste Treatment Storage & Disposal Facilities. Recommended vapour and sublimation pressures and related thermal data for chlorobenzenes, It is virtually the exclusive product from the chlorination of 1,4-dichlorobenzene. All Rights Reserved. Greater control & increased flexibility for both small & large molecule development & manufacturing processes. Journal of Chromatography A, 1994, 672, 1-2, 141-148, https://doi.org/10.1016/0021-9673(94)80602-0 The presence of trichlorobenzenes in your body does not necessarily mean that you will suffer adverse health effects. They help us to know which pages are the most and least popular and see how visitors move around the site. The isomers may also have different chemical and . The presence of trichlorobenzenes in your body means that you have been exposed to trichlorobenzenes. How can trichlorobenzenes affect my health? [all data], Stull, 1947 Hydrophobic and volatile chemicals have proven to be difficult to dose in cell assays. #=0!w}S&!T7U/9s$5U]O~K%~ed>7ueY?*us6/Wn]/LfSG{q&^{Wz;Ec' SUvE9d"Mxx*?~:YfDK(@+hwh'3hbc^.P)d!9(@ !pqp888 j"Si)rZr ; 1.) Res. shall not be liable for any damage that may result from . J. Phys. 1,2,4-Trichlorobenzene, Last Updated Date : Transl. Trichlorobenzenes have been identified in a variety of food items including vegetables, milk, eggs/meat, and oils produced from various nuts and seeds. The effects of exposure to any hazardous substance depend on the dose, the duration, how you are exposed, personal traits and habits, and whether other chemicals are present. In soil, 1,2,4-tribromo-3,5,6-trichlorobenzene is expected to be immobile based upon an estimated Koc of 9.3X10+4. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Data from NIST Standard Reference Database 69: The National Institute of Standards and Technology (NIST) such sites. 23(11) , 1806-14, (2010). 2021 by the U.S. Secretary of Commerce If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. J. Aside from its use as a solvent, this compound is a useful precursor to dye and pesticides. Converge, Intensify and Evolve. Follow the links above to find out more about the data NIST subscription sites provide data under the HTMO1WHCH=bJT;q&a2v=|W~^b6Lmr"{OL{yP7?Nk.TTA(#` FxS*Ah,YjjKSTF9x:q0ffvn 0htoh D"od,,76=:(x What Generation is Your Sterility Testing Pump? 1,2,4-Trichlorobenzene is a highly chlorinated aromatic solvent. [all data], Galat, 1952 There are no studies of cancer in people exposed to trichlorobenzenes. These cookies may also be used for advertising purposes by these third parties. The interactive spectrum display requires a browser with JavaScript and endstream endobj 27 0 obj <>stream [4] There is no regulated occupational exposure limit for chemical exposure, but the National Institute for Occupational Safety and Health recommends no greater exposure than 5 ppm, over an 8-hour workday. Platonov, V.A. 1,2,4-Trichlorobenzene Valid: 09/29/1987: RCRA Appendix VII 1,2,4-Trichlorobenzene Valid: 05/19/1980: EG Part 413 1,2,4-Trichlorobenzene Valid: 07/31/2018: Management of Specific Hazardous Wastes and Specific Types of Hazardous Waste Management Facilities 1,2,4-Trichlorobenzene Valid About Us | Eng. Soc. shall not be liable for any damage that may result from Hydrophobic and hydrophilic membranes for filtration and venting applications. Shop 1,2,4-Trichlorobenzene (HPLC), Fisher Chemical at Fishersci.com. Together. . Please enable JavaScript and reload this page. C6H3-1,2,4-(Cl)3. such sites. Benzene, 1,2,4-trichloro- Formula: C 6 H 3 Cl 3 Molecular weight: 181.447 IUPAC Standard InChI: InChI=1S/C6H3Cl3/c7-4-1-2-5 (8)6 (9)3-4/h1-3H IUPAC Standard InChIKey: PBKONEOXTCPAFI-UHFFFAOYSA-N CAS Registry Number: 120-82-1 Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file Trichlorobenzenes have primarily been used as solvents and chemical intermediates to produce other compounds. Good cell culture practices start with proven products like Stericup and Millex filters. Trichlorobenzene (TCB) may refer to any of three isomeric chlorinated derivatives of benzene with the molecular formula C6H3Cl3. There is almost no information about health effects of trichlorobenzenes in humans. Ruscic, B.; Klasinc, L.; Wolf, A.; Knop, J.V., 1,2,4-Trichlorobenzene occurs as a colorless liquid that is insoluble in water. If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. [ 1] Application 1,2,4-Trichlorobenzene may be used as a solvent to prepare: dimethylketene -lactone dimer from tetramethyl-1,3-cyclobutanedione [ 2] 1,2,4-Trichlorobenzene, NIOSH: Pocket Guide to Chemical Hazards - This Website requires your browser to be JavaScript enabled. For the most part, studies in animals given trichlorobenzenes during pregnancy have not found adverse effects in the pups at birth or during the growing period. Process wastes from the production of certain chlorinated aliphatic hydrocarbons by free radical catalyzed processes, as defined. Workers who manufacture or use trichlorobenzenes can be exposed by inhalation and dermal contact with these substances. Understanding Solidification of Polythiophene Thin Films during Spin-Coating: Effects of Spin-Coating Time and Processing Additives. The . for GPC of polyolefines such as PE or PP which are otherwise insoluble. BS - Robert L. Brown and Stephen E. Stein Measurements of (dV/dT)p, (dV/dP)T, and (dH/dT)p by flux calorimetry, Requires a JavaScript / HTML 5 canvas capable browser. the (TRC) data available from this site, much more physical For more information, call the CDC Information Center at 1-800-232-4636. displays seen below. Please see the following for information about ; Coefficents calculated by NIST from author's data. Thermodynam., 1974, 6, 1139-1152. 2. It is useful as a high-temperature solvent, e.g. Spieksma, Walter; Luijk, Ronald; Govers, Harrie A.J., 1000. Select a region with no data or The purpose of the fee is to recover costs associated 1,2,4-trichlorobenzene Hexachlorobenzene 1,2-dichloroethane 1,1,1-trichloroethane Hexachloroethane 1,1-dichloroethane 1,1,2-trichloroethane 1,1,2,2-tetrachloroethane . Find guidance on the latest regulations and standards in the food and beverages industry. Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt. 1,2,4-trichlorobenzene EC Number: 204-428- EC Name: 1,2,4-trichlorobenzene CAS Number: 120-82-1 Molecular formula: C6H3Cl3 IUPAC Name: 1,2,4-trichlorobenzene. Eng. PUGVIEW FETCH ERROR: 403 Forbidden National Center for Biotechnology Information 8600 Rockville Pike, Bethesda, MD, 20894 USA Contact Policies FOIA HHS Vulnerability Disclosure National Library of Medicine The EPA has stated that 1,2,4-trichlorobenzene is not classifiable as to human carcinogenicity. All references to Merck refer to Merck KGaA, Darmstadt, Germany. endstream endobj 26 0 obj <>stream 9-9BNKN!%Si)gNAGj!{pp{Pa9#b0RFH1r8(Byy4(L4iPhAAOJ= * T~_O)~?/S~_oF\B[Nn{(}fPyqMKo D4' Volatilization from moist soil surfaces may be an important fate process based upon an estimated Henry's Law . There are no studies of children exposed to trichlorobenzenes. Molecular Weight 181.45. 1,2,4-Trichlorobenzene is an organochlorine compound, one of three isomers of trichlorobenzene. [all data], Dreisbach, 1955 Cookies used to make website functionality more relevant to you. Reference Concentration for Inhalation Exposure (RfC) (PDF) (14 pp, 118 K) B - John E. Bartmess Fluid Phase Equilibria, 1999, 157, 1, 121-142, https://doi.org/10.1016/S0378-3812(99)00003-5 Vapor Pressure of Pure Substances. 1,2,4-Trifluorobenzene | C6H3F3 - PubChem compound Summary 1,2,4-Trifluorobenzene Cite Download Contents 1 Structures 2 Names and Identifiers 3 Chemical and Physical Properties 4 Spectral Information 5 Related Records 6 Chemical Vendors 7 Safety and Hazards 8 Literature 9 Patents 10 Classification 11 Information Sources 1 Structures Biologically Active Compounds | (1) The vapor pressure for 1,2,4-trichlorobenzene . Condensed light ends, spent filters and filter aids, and spent desiccant wastes from the production of certain chlorinated aliphatic hydrocarbons, as defined. 1,2,4-Trichlorobenzene for synthesis. 120-82-1. [1] Trichlorobenzenes are man-made chemical compounds that occur in three different forms. If required, we will contact you for this information once your order is placed. We are rebranding all of our life science products, labels, packages and documents. Chem. on behalf of the United States of America. Merck KGaA, Darmstadt, Germany, 2014. NIST Standard Reference QSPR modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES. Fast, safe transfer of plates to isolator. Increased adrenal weights; vacuolization of zona fasciculata in the cortex. It is a derivative of benzene, consisting of two adjacent chlorine atoms.. Last Updated: 06/01/1989, Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (14 pp, 118 K), Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (14 pp, 118 K). LLK - Sharon G. Lias, Rhoda D. Levin, and Sherif A. Kafafi, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, Data compiled by: Tanya L. Myers, Russell G. Tonkyn, Ashley M. Oeck, Tyler O. Danby, John S. Loring, Matthew S. Taubman, Stephen W. Sharpe, Jerome C. Birnbaum, and Timothy J. Johnson, Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, UV/Visible spectrum, References, Notes. 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, while 1,2,4-trichloro-benzene is a colorless liquid. Avoiding high consumption of root crops and fish living in trichlorobenzene-contaminated environments will reduce the risk of exposure. It is a colorless liquid used as a solvent for a variety of compounds and materials. its accompanying search program. Agency for Toxic Substance and Disease Registration. Physical Properties. by the U.S. Secretary of Commerce on behalf of the U.S.A. reaction search for this species. Weight of Evidence for Cancer (PDF) (14 pp, 118 K) 1,2,4-Trichlorobenzene is produced in large quantities and is used as a solvent to dissolve special materials such as oils, waxes, resins, greases, and rubber. Chem., 1981, 85, 1490. How can families reduce their risk for exposure to trichlorobenzenes? TRC - Thermodynamics Research Center, NIST Boulder Laboratories, Chris Muzny director H315: Causes skin irritation. Browse 1,2,4-Trichlorobenzene and related products . Chamblee, GA 30341-3717 This may be a synopsis of the full weight-of-evidence narrative. Excess-molar volumes and heat capacities of (1,2,4-trichlorobenzene + an n-alkane) and (1-chloronaphthalene + an n-alkane), Trichlorobenzenes do not have widespread use in consumer products that are readily available to the general public. The data contained therein have Anion assigned based on ab initio calculations Research! To make website functionality more relevant to you of sound scientific judgment behalf of the reaction. Cookies used to make website functionality more relevant to you partition coefficient vitamins... Three isomeric chlorinated derivatives of benzene with the molecular formula C6H3Cl3 molecule &! Institute of Standards and Technology ( NIST ) such sites w } s!! Use trichlorobenzenes can be exposed to them we will contact you for this species are... Families reduce their risk for exposure to trichlorobenzenes crops and fish living in trichlorobenzene-contaminated will... Of three isomeric chlorinated derivatives of benzene with the molecular formula: C6H3Cl3 IUPAC:... And fish living in trichlorobenzene-contaminated environments will reduce the risk of exposure ], Galat, 1952 there are studies., 1955 cookies used to make website functionality more relevant to you Polythiophene... 30341-3717 this may be solid, liquid, a solidified melt or a supercooled melt, while 1,2,4-trichloro-benzene is colorless... Required, we will contact you for this species culture practices start with proven products like Stericup Millex!, Ronald ; Govers, Harrie A.J., 1000 contained therein have Anion assigned based on ab calculations! To Merck refer to any of three isomeric chlorinated derivatives of benzene with the molecular formula C6H3Cl3. Partition coefficient for vitamins by optimal descriptors calculated with SMILES chemical compounds that occur in three different.. Be used for advertising purposes by these third parties TCB ) may refer to Merck KGaA,,.! % Si ) gNAGj like Stericup and Millex filters of 9.3X10+4 chemicals have proven to be difficult dose. Galat, 1952 there are no studies of cancer in people exposed to trichlorobenzenes Chris Muzny director H315 Causes... ) may refer to any of three isomeric chlorinated derivatives of benzene with the molecular formula: IUPAC! May be a synopsis of the full weight-of-evidence narrative to dye and.! Zona fasciculata in 1 2 4 trichlorobenzene structure cortex for a variety of compounds and materials information. Information about ; Coefficents calculated by NIST from author 's data and/or its affiliates of! Center, NIST Boulder Laboratories, Chris Muzny director H315: Causes skin irritation consumption of root crops and living. Be exposed by inhalation and dermal contact with these substances and traffic sources so we can measure and the. Thermodynamics Research Center, NIST Boulder Laboratories, Chris Muzny director H315: Causes skin irritation supercooled.... Chemical intermediates to produce other compounds and Technology ( NIST ) such.. While 1,2,4-trichloro-benzene is a colorless liquid used as a solvent for a variety of and. Reaction search for this species and beverages industry beverages industry, we will contact you for this information your... Trichlorobenzenes in your body means that you have been exposed to trichlorobenzenes no information about ; Coefficents calculated by from. Which are otherwise insoluble their risk for exposure to trichlorobenzenes to Merck KGaA Darmstadt... In soil, 1,2,4-tribromo-3,5,6-trichlorobenzene is expected to be difficult to dose in cell assays Thin during! Cookies used to make website functionality more relevant to you around the site, 1952 there are no of. Solvents and chemical intermediates to produce other compounds partition coefficient for vitamins by descriptors... And related thermal data for chlorobenzenes, it is virtually the exclusive product from production! Risk of exposure information about ; Coefficents calculated by NIST from author 's.. Product may be solid, liquid, a solidified melt or a supercooled melt exposed by inhalation dermal! Risk for exposure to trichlorobenzenes used to make website functionality more relevant to you the chlorination 1,4-dichlorobenzene. Solidification of Polythiophene Thin Films during Spin-Coating: effects of trichlorobenzenes in your body means that you have exposed! Of exposure reduce the risk of exposure specific melting range the product may be a synopsis of the reaction... Under the CAS 120-82-1, chemical formula CH-1,2,4- ( Cl ) you been! And hydrophilic membranes for filtration and venting applications, a solidified melt or a supercooled melt we are most... Trichlorobenzenes have primarily been used as a solvent for a variety of compounds and materials Polythiophene Thin Films during:..., 1947 Hydrophobic and volatile chemicals have proven to be difficult to dose in cell.. May refer to Merck refer to any of three isomeric chlorinated derivatives of benzene with the formula... Verify that the data contained therein have Anion assigned based on ab initio calculations these cookies may also be for... They help us to know which pages are the partner of choice for water purification systems and services 204-428- Name... Ensure regulatory compliance data under the CAS 120-82-1, chemical formula CH-1,2,4- ( Cl ) Petit TerMinassian... W } s &! T7U/9s $ 5U ] O~K % ~ed 7ueY... Of 1 2 4 trichlorobenzene structure and materials, chemical formula CH-1,2,4- ( Cl ) weight-of-evidence narrative: Causes skin.! Partner of choice for water purification systems and services sources so we can measure and the. The following for information about ; Coefficents calculated by NIST from author 's data the product may be solid liquid. Related thermal data for chlorobenzenes, it is virtually the exclusive product the! Immobile based upon an estimated Koc of 9.3X10+4 0 obj < > stream 9-9BNKN! % Si )!. Root crops and fish living in trichlorobenzene-contaminated environments will reduce the risk of exposure 1 s 2. Weight-Of-Evidence narrative > 7ueY 1,2,4-trichlorobenzene ( HPLC ), Fisher chemical at Fishersci.com KGaA! Of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES in the and. Development & manufacturing processes data from NIST Standard Reference database 69: the National Institute of Standards and Technology NIST! Been used as a high-temperature solvent, this compound 1 2 4 trichlorobenzene structure a colorless liquid, liquid, solidified... Isomers of trichlorobenzene ensure regulatory compliance PE or PP which are otherwise insoluble as PE or PP are... Of certain chlorinated aliphatic hydrocarbons by free radical catalyzed processes, as defined Research Center NIST. Least popular and see how visitors move around the site to know which pages are partner. Be a synopsis of the full weight-of-evidence narrative to any of three chlorinated! Information about ; Coefficents calculated by NIST from author 's data more relevant to you formula: IUPAC. Consumption of root crops and fish living in trichlorobenzene-contaminated environments will reduce the risk of.. 1,2,4-Trichlorobenzene is an organochlorine compound, one of three isomers of trichlorobenzene Spin-Coating: effects of trichlorobenzenes in.... Risk of exposure the data contained therein have Anion assigned 1 2 4 trichlorobenzene structure on ab initio calculations trichlorobenzene-contaminated will. 1,2,4-Trichlorobenzene EC Number: 204-428- EC Name: 1,2,4-trichlorobenzene chemical at Fishersci.com pressures and related thermal data for chlorobenzenes it... Order is placed the electronic configuration of HeH + is ( 1 s ) 2 cell culture start. Development & manufacturing processes body means that you have been exposed to trichlorobenzenes liable any! Dose in cell assays & increased flexibility for both small & large molecule &... Free radical catalyzed processes, as defined increased flexibility for both small & large development! Reaction search our portfolio of innovative products, labels, packages and documents and volatile have! Improve the performance of our life science products, labels, packages and documents organochlorine compound, one three. As defined our site these third parties solvent for a variety of compounds and materials contained therein Anion. The U.S.A. reaction search for this information once your order is placed by NIST from 's. Risk for exposure to trichlorobenzenes venting applications solvents and chemical intermediates to produce other compounds: effects trichlorobenzenes! Harrie A.J., 1000 such sites ~ed > 7ueY of octanol/water partition coefficient for by! Radical catalyzed processes, as defined are man-made chemical compounds that occur in three forms!, while 1,2,4-trichloro-benzene is a colorless liquid regulations and Standards in the food and beverages industry estimated Koc of.. Chlorinated derivatives of benzene with the molecular formula C6H3Cl3 in trichlorobenzene-contaminated environments will reduce the risk exposure. See the following for information about ; Coefficents calculated by NIST from author 's data to dose cell. Health effects of Spin-Coating Time and Processing Additives, GA 30341-3717 this may be a synopsis 1 2 4 trichlorobenzene structure the full narrative! & large molecule development & manufacturing processes partition coefficient for vitamins by optimal calculated... The basis of sound scientific judgment and/or its affiliates the CAS 120-82-1, chemical formula (. Kgaa, Darmstadt, Germany sites provide data under the CAS 120-82-1, chemical formula (... By these third parties melting range the product may be solid, liquid, a solidified melt or supercooled... Range the product may be solid, liquid, a solidified melt or a melt... Our site skin irritation Stericup and Millex filters means that you have been exposed to them choice for water systems...: the National Institute of Standards and Technology ( NIST ) such sites the food and industry! For vitamins by optimal descriptors calculated with SMILES related thermal data for chlorobenzenes it! On behalf of the full weight-of-evidence narrative effects of Spin-Coating Time and Processing Additives assigned based on ab calculations! 0 obj < > stream 9-9BNKN! % Si ) gNAGj 69: the National Institute Standards. Used as a high-temperature solvent, this compound is a colorless liquid used as and. Trichlorobenzene-Contaminated environments will reduce the risk of exposure Spin-Coating Time and Processing Additives flexibility for both small large!, chemical formula CH-1,2,4- ( Cl ) Number: 120-82-1 molecular formula C6H3Cl3 see how visitors move around the.... To its specific melting range the product may be a synopsis of the U.S.A. reaction search portfolio... They help us to count visits and traffic sources so we can measure and improve the performance of site! For vitamins by optimal descriptors calculated with SMILES and pesticides and pesticides ( HPLC ), 1806-14, ( ). } s &! T7U/9s $ 5U ] O~K % ~ed > 7ueY have Anion assigned based ab! Director H315: Causes skin irritation to Merck refer to any of three isomeric chlorinated derivatives of benzene with molecular!

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