Yes, they are home, but they face a Cardinals team that is hungry for success. Veteran quarterback Matt Ryan will make his debut with Indianapolis after spending the previous 14 years of his career in Atlanta. August 12, 2021: Pre-Season Week 1: August 19, 2021: Pre-Season Week 2: August 26, 2021: Pre-Season Week 2: August 31, 2021: Roster Cuts: September 9, 2021: Regular Season Week 1: . Four of the 15 remaining games currently have spreads set at a field goal or less, and there are a whopping 9 home underdogs. Week 1 NFL panel picks: Spreads, totals, locks to kick off 2021 Video is unavailable. The Titans were back in the playoffs last season and Ryan Tannehill mostly proved his excellent 2019 run was no mirage. "There was sharp play on Chiefs -3," Shelton said. That could lead to a mismatch in the trenches. Buffalo pushed the Kansas City Chiefs to overtime in last season's AFC Divisional Playoffs. NFL Lines : Moneyline: Over/Under: NBA Lines : Moneyline: Over/Under: MLB Lines : Moneyline: Over/Under: NHL Lines: Moneyline . The line has moved firmly in Buffalos direction since the open, with the Bills now 6.5-point favorites after opening at four points. This is the coming-out party for #1 overall pick Trevor Lawrence, up against a Houston defense that no longer has J.J. Watt. Las Vegas ultimately got it with a 35-32 overtime victory, winning on a final-seconds field goal. Pittsburgh's Chris Boswell hit the left upright from 55 yards with 2:27 to go but made the winning kick from 53 yards as time expired. "They're playing Raiders moneyline +150, too. LA did a reasonably good job replacing him with an accomplished veteran in Jared Cook and then nabbed a talented prospect in Georgias Tre McKitty in the third round this spring. "This one is the best two-way game so far. He is paired with first overall pick Trevor Lawrence as the new face of the franchise. 2023 Rebel Stakes Odds, Race Preview: Kentucky Derby Prep Races, FanDuel Sportsbook Releases 2023 College Football Opening Odds. This game is intriguing for two reasons. "There's hardly any money on the Over," Shelton said, while noting a $23,000 play on Under 52 and a 4/1 ticket count on the Under. Just as important, Ryan gains a talented offensive mind in Arthur Smith who helped lead Tannehills career renaissance in Tennessee as his head coach. As for the Saints, they are working with a post-Drew Brees quarterback room that consists of Jameis Winston and Taysom Hill. Opening line: Dolphins -3; Over/Under 45Time: 1 p.m. One of the top Week 1 NFL predictions the model recommends: The 49ers (-8.5) cover the spread against the Lions. Opening Total. The defense also gets a healthy Derwin James back after he suffered a season-ending knee injury for a second straight year in 2020. BETTING: FANTASY : Live Odds. But the Cowboys laid a Wild Card Weekend egg at home, losing 23-17 as 3.5-point faves against the 49ers. You'd think the defending champs opening at home would lead to L.A. being the favorite. "It'll be the biggest-teased game.". UPDATE 10 P.M. NFL Week 1 odds Updated NFL Week 1 odds. Point-spread ticket count is running almost 9/1 and money 2.5/1 on the Broncos. CBS Sports is a registered trademark of CBS Broadcasting Inc. Commissioner.com is a registered trademark of CBS Interactive Inc. site: media | arena: nfl | pageType: stories | "The Bengals will now face the seventh-most difficult schedule when looking at the opponent's season win totals. The Dolphins remain -3.5 this morning, while taking 59% of spread bets and 62% of spread dollars. Be sure to follow us on Twitter (@PFN365) to stay in the loop on all things around the NFL. "The Dolphins are a very trendy team coming into the season, with a new head coach in Mike McDaniels and a new superstar wide receiver in Tyreek Hill. The Cowboys have sky-high expectations and it all comes down to Dak. 2004-2023 CBS Interactive. The backfield was dealt a huge blow in July, when Cam Akers suffered a torn Achilles that will end his 2021 season before it began. 6-keys: media/spln/nfl/reg/free/stories, at KC returns almost all its key pieces, but they could have a No. ET WEDNESDAY: The Chargers hit PointsBet USA's NFL Week 1 odds market as 4-point favorites, then spent most of the summer at -3.5, save for a couple short stints at -3. All rights reserved. The Browns left no doubt that former head coach Freddie Kitchens was a notable part of their problem in 2019, as the transition to Kevin Stefanski couldnt have been more stark, in a positive way. UPDATE 9 P.M. Sunday, 9/12 Update: Austin Ekeler, who is listed as questionable on the final injury report of the week with a hamstring injury, appears to be on track to play and fill his usual lead-back role. The model has also made the call on who wins and covers in every other game on the Week 1 NFL schedule, and it's calling for a Super Bowl contender to go down hard. He had 26 sacks from 2019-20 before missing all but one game in 2021, and he ended up, in all places, with the rival Vikings. Gone is Teddy Bridgewater after one season despite a solid one-and-done season with the Panthers. This morning, the total returned to the 54 opener at Caesars, where tickets are running 2/1 and money 4/1 on the Over. On the other side of the field, Washington continues to ascend after an impressive playoff run last year albeit with a 7-9 record in the dumpster fire that was the NFC East. Who was the most profitable NFL team to bet the moneyline odds on each week in the 2010 regular season? However, these two squads have been the subject of plenty of chatter ahead of Week 1, primarily because of the men leading them under center. Dalton will start this game and will have top wideout Allen Robinson back. BettingData's NFL point spreads and odds page features full, compact and classic viewpoints and our members get to see historical NFL odds. Minnesota also both won and covered in last year's home game against the Packers. "We shockingly need the Over at the moment," Berg said, noting 58% of tickets on the Under is translating to a hefty 91% of money on the Under. Since then, it's dropped off to as low as 50, and it's now at 50.5. The Colts had been favored by around 2 points in this one before the initial injury to Wentz, but Seattle has been a slight road favorite over the past month and they continue to be favored at most books. In his entire coaching career beginning at Bowling Green, Meyer is 122-90-1 against the spread (ATS). Here are the Week 1 lines for all 16 NFL games, as well as some insight from our experts on games they feel strongly about ( with all odds via FOX Bet ). Philadelphia bolstered its offense by acquiring star wide receiver A.J. The Broncos opened -4.5 way back in mid-May, reached -6 in mid-August and -6.5 in late August. Take my money. Still, the road favorites are taking 85% of spread bets and 88% of spread cash. Warren Sharp gives you his sharpest betting edges for Week 1, Our Insider Patrick Everson breaks down all the hot, big-money chatter from Las Vegas. After Denver acquired QB Russell Wilson in an offseason trade with Seattle, the league decided to send Wilson and the Broncos to the Emerald City for Monday Night Football in Week 1. Meanwhile, Dallas went 12-5 SU and an NFL-best 13-4 ATS in the regular season. I anticipate that when we get closer to game time, the public is going to see those two teams and most likely bet Over. On Aug. 23, it ticked up to 42.5, and on Aug. 29, it returned to 42. Will the remaining nine home underdogs fare any better? BetMGM Nevada customers are also drilling the Over, although the total hasn't seen much movement. Of note, the Packers stole a wild 37-30 win in New Orleans last season. "Buffalo was probably the highest power-rated team in the league at the end of last season. The Steelers had what was arguably one of the more unusual seasons in franchise history in 2020, racing out to an 11-0 start before stumbling to a 1-4 mark down the stretch and then quickly getting ousted in the postseason by the Browns in a Wild Card loss at Heinz Field. And there are plenty more intriguing matchups. Seattle returns all its key pieces, with running back Chris Carson somewhat surprisingly brought back to helm the backfield and DK Metcalf and Tyler Lockett once again set to serve as Wilsons top two targets. In the backfield, Kenyan Drake was swapped out for James Conner in a move that could prove to be a wash. Arizona made one of the more intriguing free agent offensive additions in multi-time Pro Bowler A.J. San Francisco 49ers Super Bowl Odds: Can Trey Lance or Brock Purdy Lead the Niners to Super Bowl 58 Victory? Jaylen Waddle will join fellow new arrival (via free agency) Will Fuller to give the Fins the outside speed theyve sorely lacked for some time. I dont expect this to be a big decision for the book, but I do think its one of the most interesting games of Week 1. Miami opened and closed the regular season against New England and went 2-0 SU and ATS. 1 option Terry McLaurin. Make no mistake, this Jaguars team is loaded with untapped potential. The Football Team was the proverbial big fish in the small pond that the NFC East became last season after Prescott went down for the Cowboys. The Bucs are currently at -1.5, matching The SuperBook's opener in the NFL Week 1 odds market. "Sharp play on Over 52. No one's playing the Patriots right now," Shelton said. ET SUNDAY: Kansas City is out to -4.5 at BetMGM Nevada, after opening -3, reaching -3.5 on Aug. 22, and going to -4 and -4.5 on Aug. 31 . The return of versatile running back Christian McCaffrey, who missed much of 2020 with multiple injuries, also looms large. Ryan is on the wrong side of 30, but he can decimate this Eagles defense in Week 1. Secondly, is what will be occurring under center for the Houston Texans. They blew up one of the best offensive lines in football this offseason. But the Raiders had a short playoff stay, losing at Cincinnati in the AFC Wild Card round 26-19 as a 6-point pup. Typically, a rookie signal-caller and head coach in their first week is an instant fade. However, Washington, which opened as a 1.5-point favorite before seeing the game move to a Pick Em on multiple sportsbooks throughout the week, is back to being favored by one on Sunday morning. 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